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中国科学家制造基因改良人类血管细胞

文章来源:admin    时间:2019-01-23

  Chinese scientists produced the world's first genetically-engineered human blood vessel2 cells, providing a promising3 option for therapeutic4 use.   中国科学家制造出世界第一个基因工程人类血管细胞,为相关治疗带来了希望。   The study published on Thursday in the journal Cell Stem Cell showed that human vascular5 cell function can be enhanced by editing a single longevity-related gene1.   Scientists from the Institute of Biophysics of the Chinese Academy of Sciences (CAS), Peking University and the Institute of Zoology6 of CAS targeted a gene called FOXO3, an important regulator to delay cellular7 aging, resist stresses and enhance cardiovascular balance.   The technique can also resist the cells' transformation8 into tumors. The risk of tumor9 transformation used to be a major concern for the application of the gene-editing technology.   The researchers tested it in a mouse model with blood-shortage or ischemic injury and found that those cells promoted vascular regeneration and resisted tumor transformation both in vitro and in vivo.   They expected to use gene-editing strategies in the future to produce high-quality, safe human vascular cell grafts10 in a large-scale and standardized11 manner.
1 gene      n.遗传因子,基因 参考例句:
  • A single gene may have many effects.单一基因可能具有很多种效应。
  • The targeting of gene therapy has been paid close attention.其中基因治疗的靶向性是值得密切关注的问题之一。
2 vessel      n.船舶;容器,器皿;管,导管,血管 参考例句:
  • The vessel is fully loaded with cargo for Shanghai.这艘船满载货物驶往上海。
  • You should put the water into a vessel.你应该把水装入容器中。
3 promising      adj.有希望的,有前途的 参考例句:
  • The results of the experiments are very promising.实验的结果充满了希望。
  • We're trying to bring along one or two promising young swimmers.我们正设法培养出一两名有前途的年轻游泳选手。
4 therapeutic      adj.治疗的,起治疗作用的;对身心健康有益的 参考例句:
  • Therapeutic measures were selected to fit the patient.选择治疗措施以适应病人的需要。
  • When I was sad,music had a therapeutic effect.我悲伤的时候,音乐有治疗效力。
5 vascular      adj.血管的,脉管的 参考例句:
  • The mechanism of this anomalous vascular response is unknown.此种不规则的血管反应的机制尚不清楚。
  • The vascular changes interfere with diffusion of nutrients from plasma into adjacent perivascular tissue and cells.这些血管变化干扰了营养物质从血浆中向血管周围邻接的组织和细胞扩散。
6 zoology      n.动物学,生态 参考例句:
  • I would like to brush up my zoology.我想重新温习一下动物学。
  • The library didn't stock zoology textbooks.这家图书馆没有动物学教科书。
7 cellular      adj.移动的;细胞的,由细胞组成的 参考例句:
  • She has a cellular telephone in her car.她的汽车里有一部无线通讯电话机。
  • Many people use cellular materials as sensitive elements in hygrometers.很多人用蜂窝状的材料作为测量温度的传感元件。
8 transformation      n.变化;改造;转变 参考例句:
  • Going to college brought about a dramatic transformation in her outlook.上大学使她的观念发生了巨大的变化。
  • He was struggling to make the transformation from single man to responsible husband.他正在努力使自己由单身汉变为可靠的丈夫。
9 tumor      n.(肿)瘤,肿块(英)tumour 参考例句:
  • He was died of a malignant tumor.他死于恶性肿瘤。
  • The surgeons irradiated the tumor.外科医生用X射线照射那个肿瘤。
10 grafts      移植( graft的名词复数 ); 行贿; 接穗; 行贿得到的利益 参考例句:
  • He's gone to London for skin grafts on his thighs. 他去伦敦做大腿植皮手术了。
  • Her burns were treated with skin grafts. 她的烧伤是用植皮方法进行治疗的。
11 standardized      adj.标准化的 参考例句:
  • We use standardized tests to measure scholastic achievement. 我们用标准化考试来衡量学生的学业成绩。
  • The parts of an automobile are standardized. 汽车零件是标准化了的。

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